Died at his home in Richmond, the city of his residence since 1790. He came from Augusta with his famous bride and they were a welcome addition to Richmond society. After having done his duty faithfully as an officer throughout the Revolutionary War and passed unhurt through all its peril, he was, suddenly, when in full health killed by a fall from his horse in the streets of Richmond. But death however sudden never finds the sincere and fervent Christian unprepared and such was he. His name is perpetuated in that the eminence "Gamble's Hill" upon which his residence stood is called that still. He left a widow in Catherine Gamble who died in 1830. She was the daughter of Major John Gratton. She was noted for her beauty and courage. She once rode through the night to warn her pioneer neighbors of an impending Indian raid. There was no wife more devoted.

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Robert Gamble, born on a farm in Augusta County in 1754, became an officer of the first company raised in the county. During the war,
he was taken prisoner in South Carolina and was confined on a British vessel in Charleston. According to Joseph Waddell’s Annals of
Augusta County Virginia from 1726 to 1871, after the war, in 1792 or
early in 1793, he left the Shenandoah Valley and moved to the City of
Richmond, where “he became a prosperous business man and influential citizen. His residence in Richmond was on the eminences called for him, Gamble’s Hill, and his business was conducted in a large building at the corner of Main and Fourteenth Streets… Colonel Gamble was in the habit of riding on horseback every morning from his residence to his counting-room. On the 12th of April, 1810, as he was thus on his way, reading a newspaper, some buffalo skins were thrown from the upper window of a warehouse he was passing, his horse took fright, started, and threw him, which produced concussion of the brain, and terminated his life in a few hours.”