He was the son of Alfred and Eugnie Berube. He had a sister named Mary Ann. He completed 3 years of high school, was single without children. He worked as a Machinist prior to enlisting
He enlisted as a Private on 16 Nov 1940 for the US Army Air Corp in Boston, Massachusetts. After his initial basic training, he was later assigned to the 8th Bomber Squadron, 3rd Bomber Group, Light in the Pacific Theatre.
On Oct. 24, 1943, a B-25D-1 Mitchell bomber crewed by these airmen departed Oro Bay Airfield in New Guinea on a bombing run of enemy targets in Rabaul. As the aircraft neared its target, it was attacked by Japanese fighter aircraft. Crewmen from other aircraft said they saw the B-25 crash near a plantation at Kabanga Point. There were no survivors. The crew members killed in the crash were 1LT Robert H. Miller, of Providence, Rhode Island; 2LT Robert L. Hale, of Newtonville, Massachusetts; SSG Joseph A. Berube, of Fall River, Massachusetts; SSG Glendon E. Harris, of North Monmouth, Maine.
SSG Berube was listed as missing in action-presumably killed in action on 24 Oct 1943. His name appears on the Tablets of the Missing located at the Manila American Cemetery, Manila, Philippines. He received the Distinguished Flying Cross, Purple Heart posthumously.
SSG Berube's were recovered. In 1946 and 1947, Australian War Graves search teams recovered some of the crew's remains from the crash site. Identifications were not possible at the time and the remains were ultimately buried at the Manila American Military Cemetery in the Philippines.
From 1999-2000, the Joint POW/MIA Accounting Command (JPAC) led a joint U.S. and Papua New Guinea (P.N.G.) investigation and excavation of a WWII-era crash site in East New Britain Province. One joint team interviewed individuals having information on the crash, including an eyewitness who said he saw the B-25 crash near his village. Another individual found and buried human remains at the crash site in the mid 1990s. The team surveyed the site and found aircraft wreckage, human remains and personal effects. A second joint team excavated the site and recovered additional human remains and crew-related artifacts from the wreckage field.
In 2004, an anthropologist from JPAC's Central Identification Laboratory (CIL) exhumed the graves at the Manila American Military Cemetery where he recovered the remains buried there in the 1940s.
Among dental records, other forensic identification tools and circumstantial evidence, scientists from JPAC and the Armed Forces DNA Identification Laboratory also used mitochondrial DNA in the identification of the remains.
SSG Berube's remains were returned to his family. He was buried in Saint Patrick's Cemetery, Natick, Middlesex, Massachusetts