Samuel Tredwell was born in 1763 in Hemstead, Nassau County, Long Island, NY, the eldest of 9 known surviving children (6 boys/3 girls) born to Dr. Benjamin Tredwell, Jr, and his wife, Elizabeth Seabury.
He is descended on both sides of his family tree from prominent and notable New Yorkers. He was the paternal grandson of Benjamin Tredwell, Sr. & Phoebe Platt of Long Island; and the direct descendant of this family's patriarch Edward Tredwell, who first came to Long Island from Ipswich, MA ca. 1640. He was the maternal grandson of Rev. Samuel Seabury and Elizabeth Powell of Hemstead, NY. Tthrough the Seabury line, he was the 7th a direct descent from John Alden and Priscilla, the "Puritan Maid".
In 1785, the 22 year old left New York for the thriving southern seaport of Edenton, Chowan County, NC where President Washington had appointed him Collector of the Port of Edenton, an office he held until his death. Adding to his prestige, he was later named State Commissioner of North Carolina in 1818.
In about 1790, he married Helen Scrymgeoure Blair, the 27-year old daughter of wealthy Scottish immigrant merchant, George Blair, and his wife Jane/Jean Duncan Johnston, who was sister to Gov. Samuel Johnston of North Carolina.
Samuel and Helen would become parents to 4 known surviving children: Elizabeth H. (1791-1792), Margaret Penelope (1795-1849), Frances Johnston (1797-1865), and James Iredell Tredwell (1799-1846).
Samuel and Helen were owners of the now historic "TREDWELL HOUSE" on West Eden Street, Edenton. The earliest record of this property is a grant in 1757 to the Honorable Peter Henley, Esq., Chief Justice of North Carolina. In 1774, his son John appointed Samuel Johnston to sell all his property in the state; the Edenton lots, however, were still unsold when the Revolution began, and were confiscated because Henley was an Englishman. In 1787 these lots, unimproved, were bought by William Borritz, who built the present house. By 1800 it became the home of Samuel Tredwell, Collector of the Port of Edenton and Roanoke.
Samuel was widowed in 1802 when his wife of 12 years died at age 39. In 1804 he married Frances Pollock Lenox, daughter of Dr. Robert E. Lenox & Frances Pollock, great granddaughter of Gov. Thomas Pollock of NC. This marriage produced no children.
Samuel Tredwell died in 1826 at age 63 and was buried near both his wives in the Johnston Family Cemetery on "Hayes Plantation", in Edenton, the home of Gov. Samuel Johnston (1733-1816).
As for his children, daughter, Elizabeth, died at age 18 months and is buried in Philadelphia, where it is presumed the family was visiting at the time of her death. Margaret never married and is buried in Raleigh near her sister, Frances Iredell.
Daughter Frances Johnston Tredwell married and had children, becoming the wife of Gov. and U.S. Senator James Iredell, Jr. She is buried in Old City Cemetery in Raleigh.
The only son, James Iredell Tredwell
married Mary Bonner Blount in 1827 and as father to 7 known children. He removed the family to Brooklyn, NY where he died in 1846 at age 47. Following his death his widow and children returned to North Carolina.