Samuel is buried next to his wife Susan (Masters) Clark, whom he married on 2 Dec 1809 in the Pendleton District of South Carolina.

According to her War of 1812 widow's pension application, Susan Clark first declared that her husband, Samuel Clark, served in Capt. E. Moore's Company, South Carolina Militia. Her application was filed 14 Oct 1874 and rejected 24 July 1877, the main reason being that his name did not appear on any of the company's rolls. Susan tried again, this time saying that Samuel served under Capt. James Thompson's Company in the South Carolina Militia in the War of 1812. To clarify, a lawyer wrote on her behalf and enclosed a letter supposedly showing that Samuel Clark belonged to "Capt. James Thompsons' Artillery Company, Col. Enoch Moore's Regiment, of the South Carolina Militia." The War Department still could not find Samuel's name on any roll as proof, and her application was again rejected. Considering that Samuel and Susan were married at the time of the War of 1812, she would have remembered if he did or did not serve. He must have fought in some South Carolina unit, but since the unit was never identified, Susan was never able to collect her widow's pension.

Samuel and Susan (Masters) Clark had a large family. Susan stated in her application that they had had 15 children, but the only known ones are John C. Clark, Presley R. Clark, Samuel C. Clark, Henry Gaines Clark, James Washington Clark, Warren Jackson Clark, Francis Marion Clark, Mary A. Clark, Elizabeth Clark, and twins Turner P. and Amos J. Clark. Most lived in Henry, DeKalb, and Meriwether Counties of Georgia.

Note: In the book Memoirs of Georgia, Vol. II, (Atlanta, GA: The Southern Historical Association, 1895) on pp. 503-504, there is a sketch about W. J. Clark, son of Henry Gaines Clark, who was a son of Samuel and Susan (Masters) Clark. This sketch states that W. J.'s grandfather was a "Thomas Clark" born in England, who settled first in South Carolina, married, and then migrated to Georga where he lived in Meriwether Co., Coweta Co., Cherokee Co., and back to Meriwether Co. No sources are given for any of this information. It's certain that Samuel was not born in England. He said he was born in Virginia on the 1850 census, and that is what his children said in the 1880 census. No one ever said he was born in England. As for being called Thomas, there seems to be no other source that ever called him that, and none that called him "Samuel Thomas Clark." In every other record, he was simply "Samuel Clark."