Ambrose Crum was the son of McDonough and Margaret Holcomb Crum, who also had three other children: George H., Amanda Lucinda, and LaFayette. Ambrose's mother Margaret died when Ambrose was two years old. His father William was remarried to Harriet McGowan Crum, and they had two children: daughter Alphena and son Taylor.
Ambrose died on 6 Oct 1852 at the tender age of 6. His baby sister Alphena died two weeks later on 20 Oct 1852 at age 1-1/2. Just three weeks after Alphena's death, brother Taylor was born on 6 Nov 1852. It surely must have been a bittersweet time in the life of the Crum family.