Nathaniel Pope Sr. in his will probated in 1660 in Westmoreland County, Va. named his sons, Thomas and Nathaniel, and his sons-in-law, John Washington and William Hardridge (Hardich).

Nathaniel Pope, Jr., the second son of Lt. Colonel Nathaniel (c1610-60) and Lucy Pope, was born c1640, at St. Mary's, Maryland and otherwise lived and died at the family seat, Popes Creek, Westmoreland County, Va. He obtained patent on Hollis Creek for 1050 acres in 1661. He married Mary Baldridge (c1641-77), daughter of James (-1659) and Dorothy Baldridge (-1662). Her sister, Frances (-1698), married Capt. Daniel Sisson/Lisson who was a magistrate and known for his knowledge of the languages of the different Indian tribes. Nathaniel Pope, Jr. died early and left an only son, Nathaniel Pope III (1660-1719). Mary Baldridge later married a Nicholas and had a son Lewis Nicholas. She married again in 1672, David Wickliffe (1640-) who may have been an ancestor of the Wickliffes in Kentucky. Their children were David, Robert and Deborah Wickliff.

Nathaniel Pope, Jr. died in 1670. His wife, Mary Baldridge, died in 1677. They are buried ___.

See William Armstrong Crozier, ed., Virginia County Records, New Series, Westmoreland County (Baltimore: Genealogical Publishing Co., 2001 (Rprt.)), 2, 11; George W. Beale, "Col. Nathaniel Pope and His Descendants," William & Mary College Quarterly XII: 192-196, 250-253 (1903-1904)(states Nathaniel Pope married Mary Sisson whose brother was Daniel Sisson. However, it is believed Daniel Sisson was instead Mary's brother-in-law as James Baldridge left his property to Daniel Sisson); James Houston Barr III, Lt. Colonel Nathaniel Pope, c1610-1660, of Virginia, Ancestor of Washington, Governors and Legislators, History of His Descendants (Louisville, Ky. 2018), 33.