Charles Lewis Clay was born in Montgomery County, Virginia. His parents were Mitchell Clay, Jr. and Judah Clay. In 1824 he was living in what would become Wyoming County, Virginia (now West Virginia) and married his first cousin, Aura Stewart. She was the daughter of Captain Ralph Stewart and Mary Clay Stewart. His father, Mitchell, and Aura's mother, Mary, were brother and sister.

In 1847 Charles and his family moved to Fayette County, Virginia (now Raleigh County, West Virginia). They settled first on the waters of Breckenridge Creek. Later he made his permanent home in Marsh Fork District and lived there until he died at Bee Branch, West Virginia.

Charles and Aura had 15 children. This is a list of the known children:
Rebecca Jane Clay
Drucilla Clay
Greenville Wyatt Clay
Henry Byron Clay
Mitchell M Clay
James Mandeville Clay
Ralph Stewart Clay
Lucinda B Clay
William Kemper Clay
Mary Caroline Clay
Charles Clay
Araminta Clay

Charles Lewis Clay was born in Montgomery County, Virginia. His parents were Mitchell Clay, Jr. and Judah Clay. In 1824 he was living in what would become Wyoming County, Virginia (now West Virginia) and married his first cousin, Aura Stewart. She was the daughter of Captain Ralph Stewart and Mary Clay Stewart. His father, Mitchell, and Aura's mother, Mary, were brother and sister.

In 1847 Charles and his family moved to Fayette County, Virginia (now Raleigh County, West Virginia). They settled first on the waters of Breckenridge Creek. Later he made his permanent home in Marsh Fork District and lived there until he died at Bee Branch, West Virginia.

Charles and Aura had 15 children. This is a list of the known children:
Rebecca Jane Clay
Drucilla Clay
Greenville Wyatt Clay
Henry Byron Clay
Mitchell M Clay
James Mandeville Clay
Ralph Stewart Clay
Lucinda B Clay
William Kemper Clay
Mary Caroline Clay
Charles Clay
Araminta Clay