John was one of five known children born to William and Ann (Turner) Hacker. His siblings were:
William, b. 1739
Elizabeth, b. ca 1741; m. John Freeman
Nancy Ann, b. ca 1745; m. James Keith & Col. Claypool
Mary Polly, b. 1747; m. John Bush

John married Margaret Ann Sleeth in 1765 in Loudon Co., VA. She was the daughter of John and Mary (Wallace) Sleeth.
They were the parents of eleven children:

1. Mary Ann, b. ca 1768; m. Edmund West, Jr.
2. William, b. 1770; m. Adah West
3. Jonathan Daniel, b ca 1772; m. Hannah Bennet
4. John Turner Jr., b. 1773; m. Mary Susannah Smith
5. Sarah, m. David Smith
6. Margaret, b. 1776; m. Peter Hardman
7. Alexander b. 1781 m. Betsy McNemar
8. Elizabeth, b. 1784; m. Henry Hardman
9. Absolam b. 1787 m. Elizabeth Kirkendall
10. Thomas S b. 1790 m. Margaret Keith
11. Mary Ann, b. 1793; m. John Helmick.

Two of these daughters, Mary Ann Hacker West and Margaret Hacker Hardman, were slain and scalped by indians.

When John moved and located his family on Hacker's Creek in 1769, he brought his parents with him and took care of them until they died; the father in 1772 aged 92 years and the mother in 1778. This family was the first family to live on Hacker's Creek, and their second child, William, was the first white child born there.

John served "under the command of Captain James Booth who commanded a Company of Militia in defense of that part of the Western frontier of West Augusta which now comprises the Counties of Harrison and Lewis. He served two long years (1782-1784) with George Rogers Clark on his campaign against the British at Kaskaskia and Vincennes. He served at various times as a magistrate and sheriff. He was appointed by the Harrison County court, together with John Waggoner and Jacob Cozad, to represent the county at the Greenville Treaty in 1795.

John's Will was written, signed and witnessed in Lewis Co., VA on 18 March 1822, and it lists all eleven of his children.

Info provided by Jerry Sayre FAG#47013714 :
Margaret Hacker Hardman was not slain by Indians, although she was partially scalped. She lived to have 10 children including two sets of twins.
Jerry Sayre 5x great grandson of John Hacker.