Ninth of twelve children of John Nesbitt Nash (1786-1864) and Hannah Harriett Abercrombie (1786-1840). Of the twelve children, he was the last one to pass on.

On 6 August 1843 John married Rebecca Ursula Shaw (1819-1887). The daughter of John "Pleasant" Shaw (1790-1876) and Mary Caroline Poole (1793-1850) of Princeton, South Carolina. John's brother Thompson Edward "T. E." Nash (1811-1889) officiated the wedding. Thompson's wife Elizabeth Marian (Shaw) Nash (1816-1894) was the sister of Rebecca (Shaw) Nash. Nash brothers married Shaw sisters. Their wedding was held at the home of John's maternal-uncle James Abercrombie (1798-1880) in SW Campellton, Campbell County, Georgia. The James Abercrombie house stood on what is now Brown's Lake Road, in the Cedar Grove Community of NW Fairburn, Fulton County, Georgia.

After their marriage, John and Rebecca settled in Fayetteville, Georgia where McDonough Road dead-ends to State Route 54. Nash Creek that runs under Highway 54 was named after him. Most of John's siblings settled along McDonough/Jonesboro Road in Henry County. The John Nash House once stood on State Route 54, across the street from the intersection with Callaway Road.

Four pregnancies, but only one daughter growing to adulthood.

1.) infant girl Nash (1845-1845) who died at birth;

2.) infant girl Nash (1848-1848) who died at birth;

3.) infant boy Nash (1851-1851) who died at birth;

4.) Mary Catherine Nash (1854-1924) who married Elias Smith "Eli Smitty" HUGHEN (1848-1924).

Right after their 44th wedding anniversary, Rebecca contracted pneumonia and passed away from complications. She was originally buried in their J. C. Nash Family Cemetery.

On 17 June 1888 in Fayette County, Georgia John married second, his neighbor, widower Nancy Ann Sophronia (Holcomb) LEWIS (1848-1900). The daughter of Clayton Holcomb (1816-1878) and Elizabeth Vernon (1822-1867) of Haralson, Georgia.

The J. C. Nash Cemetery is the family cemetery of John and Rebecca Nash. Their home once stood in front of the cemetery, closer to Highway 54, where a red Heating/Cooling business now stands. The home burnt down in the 1950's after a small plane crashed into the front yard. NASH, HUGHEN, HILL, CAMP, CALLAWAY, LEWIS, GREEN, CATO, MURPHY, ALLEN, COTTON, BELISLE and others were known to have once been buried here. It is sometimes mislabeled as the "GNash" Cemetery since an old carved sign once read, "J. C. Nash". The "J" and the "C" were connected like the Georgia Tech symbol today. John and Rebecca's original graves were covered by a small awning built by descendants. Many members of the family were interred here, but since it was not maintained, it became very overgrown in the mid 1900's. Many graves, sadly, were only marked by field stones or crudely made markers. There is even a story passed down through the Nash family about a little girl that died during the time her parents were traveling through Fayetteville and they received permission from John to bury her here, marked only with field stones. By the 1960's and 1970's many were being exhumed and moved. In 1976, John's great-grandson, Howard Elihu Nash (1895-1993) had John, Rebecca and several Nash and Hughen family members exhumed and moved across the street to the Camp Memorial Park Cemetery with all new markers, but others are still buried here, including members of the Hill Family. John's newer marker does not have his birth date of 8 May 1821 and its never been corrected. Kudzu and underbrush at times, have consumed its existence. In the 1990's a chain-link fence was added to define it's borders.