Born the second child to Michael Kinney Van Fleet and Alletta Shirts Van Fleet. He was named after his grandfather Adrian, and I am certain he was given the name Adrian, however, over time, he came to use the spelling Adrain. Census records show fluctuation between Adrian and Adrain as his spelled name.
His siblings were: Elizabeth S Van Fleet Sarah J Van Fleet Joseph T Van Fleet Roseniah J Van Fleet Hanford C Vanfleet
He married Catherine Van Fleet in 1870. After the passing of his father, his mother Alletta lived with he and Catherine, at least as of the 1880 census.