The son of John Newton Ayers and Dora Jane Darnell Ayers. The brother of John Roy Ayers . Married Maxie Williams Ayers.
He was the father of John Howard Ayers, Geneva Westmoreland, Francis Stacey and Sarah Hellon Fox. His grandchildren are John Michael Ayers, Kenneth Howard Ayers, Darrell Thomas Fox, Landis Timothy Fox, David Howard Westmoreland, Steve Stacey, Ronnie Stacey, Connie Stacey , Janice Westmoreland Sherer, Gloria Westmoreland.
Ralph Thomas Ayers was a Baptist. He attended the Mooresville Methodist Church and was a farmer in the Mooresville community of Marshall County (Lewisburg) Tennessee.