Mar. 19, 1700 Ipswich Essex County Massachusetts, USA
Jun. 25, 1740 Cambridge Middlesex County Massachusetts, USA
Mrs. MARGARET HOLYOKE, Wife to ye Revd. Mr. EDWARD HOLYOKE President of Harvard College (and youngest Daugtr. of ye Honble. Collo. JOHN APPLETON of IPSWICH late Deceas'd)Died June 25th A.D. 1740 having enter'd Her 40th Year ye 19th Day of March last.
Parents: John Appleton & Elizabeth Rogers Husband: Edward Holyoke