John B. Allison married Elizabeth Mosby Woodson on November 14, 1850 in Monroe County Missouri.
John B. Allison's parents, Alexander & Jemima Crawford Allison, settled in Boone County about six miles north of Columbia on the Boone's Lick Road in 1815.
John's mother died when John was eight years old. John apprenticed out to a tanner and followed that trade until he was 21. He was an avid reader and at age 22 was teaching school in Florida Monroe County Missouri.