Verne's father, Joseph Byrne, owned and operated the Wood Davis Hardware Store, as well as other businesses in Santa Fe and a ranch in the Cerrillos Hills. Son of Lydia "Donnie" Laird O'Niel.
Daughter, Nelle, and her daughter, Lydia, and son, Verne, came from Beardstown, Illinois, where Verne was born. They lived with O'Neill and Donnie in the great red brick house (the mine manager's house), demolished in the 1970s, at the Cash Entry Mine.
Nelle and her children later moved to Denver, but the family returned to the Cerrillos area in 1921, when Verne was 13.
Verne attended grade school at Cerrillos, and high school at the Los Alamos Boys Ranch where he was a member of the third graduating class. Verne attended New York University and later graduated from the Ryan Flying School in San Diego, California. He returned to the area and operated his own airport where the College of Santa Fe is now located. He used his Great Lakes plane for charter flights, aerial photography, and flying instruction. He worked for The New Mexican, as assistant editor of the Spanish edition, El Nuevo Mejicano.
Verne also owned Byrne's Wrought Iron of Distinction, and made many of the iron works around the plaza and La Fonda Hotel in Santa Fe. After World War II, he was associated with the early uranium mining industry in New Mexico. In the 1950s he was a mining engineer with the Santa Fe Railroad at Haystack Mountain near Grants.
Verne continued the family mining tradition and besides the claims he inherited from O'Neill, he pruchased and worked a number of Cerrillos claims, including the Blue Bell, Mina del Tiro, Pennsylvania, and Marshall Bonanza mines.
In 1956 Verne Byrne, with his wife, LaVerne, and daughter, Sharon, moved from Santa Fe to Ojo Caliente, where he owned and operated Los Compadres Gem and Mineral Shop and he made jewelry. Verne also operated a mica mill and worked mica and pegmatite claims in the Petaca area. The patented Globe Claim is still owned by his widow, LaVerne, at this writing. While in Santa Fe, Verne was president of the Santa Fe Gem and Mineral Club and was often invited by various groups to give talks on turquoise, until his death in November, 1981.
Verne Byrne considered Michael O'Neill his grandfather. Both Verne and O'Neill are buried in the Protestant cemetery at Cerrillos. The marker on O'Neill's grave is gone, and its location in the cemetery has been unknown to the family for several decades. Verne is buried in the Laird family plot.