Ladson was the son of Paris Hickman and Mary Margaret "Polly" Alexander. The Hickman family lived near what is now the Kershaw/Lee County, So. Carolina line near Bishopville. At sometime after 1830 the Hickman family moved to Pickens Co., Alabama, and after 1830 were living in Neshoba Co., Mississippi, where Ladson married Rebecca Josephine Ross. Six of their children were born in Neshoba county, and after removing to near Pocola, Choctaw Nation, Indian Territory just after the Civil War, five more children were born.
During the Civil War, Ladson Hickman enlisted in the Confederate Army and served as a Pvt., Co. E, 5th Reg't, Mississippi Minute Men, also known as "Miss. State Troops". He received an indefinite furlough on Oct 21, 1862. (Reason not known). However, he had four children at this time.
In 1867, together with other Hickmans, Morrises, Moores and Donalds and their wives and children, some six hundered people in all, left Mississippi because of the terrible destruction left by Sherman and the so-called "Reconstruction" program. Most of these families settled near Fort Smith, Ark. and the Pocola, I.T. area. Ladson farmed in the Poteau River area near Pocola until he died in 1895 and the remaining family members moved to Spiro, I.T. and other locations in the Indian Territory.