Dr. John Millar had previously lived in South Carolina where he had met and married his wife, Elizabeth Payne, daughter of a wealthy South Carolina family. Between 1817 and 1820, Dr. Millar moved with his wife two children, Daniel and Nancy, to Morgan County, Alabama, near Decatur, where they lived until 1831 when he migrated to Texas. The Millars traveled by riverboat down the Mississippi to New Orleans, their entourage consisting of six children and a few slaves, and from that point completed the trip by ship, perhaps to the mouth of the Colorado. Dr. Millar settled on the west bank of the Colorado River at the Atascosita Crossing, located about four miles south of present-day Columbus, TX. While in New Orleans, the family contracted smallpox. Shortly after arriving in Texas, two children, William and Julia, died of the disease. Dr. Millar lived only a few months after. He died on October 21, 1831. His widow, Elizabeth, married Jacob Betts shortly thereafter.

Elizabeth Payne married on Nov 11, 1814 to Dr. John Millar and had 6 children together. After John died in October 1831, she married Jacob Betts. She died soon after in 1837 and her younger son John Jr. and daughter, Elizabeth were raised by Nancy Millar Alley, (wife of Abram Alley).

Her second husband was Jacob Betts...

Texas State Historical Association -

JACOB BETTS (unknown–1837).Jacob Betts, one of Stephen F. Austin's Old Three Hundred colonists, came to Texas from Georgia as early as 1822 and voted in an alcalde election in August 1823. As one of the Old Three Hundred he received title to a sitio now in Matagorda County on August 19, 1824. In May 1825 he wrote to Austin stating that he had spent three years "in poverty and misery" in Texas, where he had come looking for better times, and that he was dissatisfied with "soft words and fair promises" and wanted more land. In 1826 he sold half a league to James Grant (possibly Dr. James Grant). Thomas M. Duke wrote Austin from Bay Prairie on January 3, 1827, that the Karankawa Indians had destroyed the Betts homestead, and on May 13, 1827, Betts was among those signing a treaty with the Karankawas at La Bahía. In 1836 Betts was among the men serving in Albert Clinton Horton's company, the Matagorda Volunteers, under James W. Fannin. He died on October 31, 1837, and his daughter Mary Betts Kincheloe was administrator of his estate.