The first wife of William Nelson Hamilton was Cathrine E. Rinehart Hamilton. They were married 4 Nov 1850. There were no children, after her death, William married again to: Mary E. Crick; on 12 Aug 1853; there were at least five children born to this marriage.
After Mary's death he married again Elinore Cook, 11 Feb 1869. I believe there were five children born of this marriage.