He was the son of Isaac & Talitha (Cloud) Cantrell.
He married Martha Savage about 1789 in North Carolina. Shortly after his marriage he moved to the old 96th district in South Carolina. Here, in July of 1794, he bought 200 acres of land on Little Buck Creek.
They were on the 1800 census for Spartanburg Dist., South Carolina. In 1805, he migrated to middle Tennessee. In 1806 he signed a petition for the establishment of Warren County.
In 1824 he had a land entry in a part of Warren County which is now in DeKalb County. They were members of the Bildad Baptist Church. He died in about 1825.